Network-Driven Drug Discovery

Dr. Jonny Wray — CTO at e-therapeutics


  • Jonny Wray is the CTO of e-therapeutics, a drug discovery company specializing in network-driven drug discovery.
  • Network-driven drug discovery is an in-silico approach that applies network biology and systems thinking to reduce late-stage clinical failures in drug development.
  • The approach focuses on altering phenotypes at the molecular level by manipulating networks through drug targets and transduction mechanisms.
  • e-therapeutics gathers data from various sources, including protein interactions, text mining, and cell-specific experiments, to create a comprehensive database of molecular interactions.
  • The company utilizes compound databases and analyzes their impact on the network to identify potential drug candidates, validate targets, and drive therapeutic programs.

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